{"product_id":"agent-nateur-duo-holi-mane-holi-radiance","title":"Duo Holi (Mane) + Holi (Radiance)","description":"\u003cp\u003eThis duo brings together Agent Nateur's two beauty-from-within supplements: Holi (Mane), made with marine collagen and pearl powder, and Holi (Radiance), made with MSM and phytoceramides. Clinical studies show the benefits of combining MSM and collagen: improved dermal density, skin hydration and texture, and reduced wrinkle volume and depth.\u003c\/p\u003e\n\u003cp\u003eCollagen is the most abundant protein in your body. It acts as a \"scaffold\" and makes up connective tissue. It accounts for 70% of your dermis (the middle layer of the skin), and high collagen levels in the body help prevent bone loss and support joint regeneration. It also supports the health of hair, skin and nails. As we age, collagen levels naturally decline, which is why supplementing with high-quality collagen can help prevent visible signs of aging.\u003c\/p\u003e\n\u003cp\u003eMSM is a stable sulfur compound often called the \"beauty mineral\". Studies confirm its ability to improve skin hydration and elasticity. MSM also supplies sulfur to keratin, a protein essential to hair growth, regeneration and overall health. MSM is anti-inflammatory and antioxidant. It is also a precursor to glutathione, which helps the body detoxify and fight candida overgrowth, and helps relieve joint, inflammatory and chronic pain.\u003c\/p\u003e\n\u003cp\u003ePhytoceramides are the second ingredient in Holi (Radiance). Dr. Will Cole suggested adding them because they are a lipid naturally found in the skin that supports its structure and function. As we age, we lose ceramides: the moisture barrier weakens and skin texture changes (sagging, fine lines and wrinkles). Taken orally, phytoceramides deliver new ceramides to the skin through the bloodstream and help restore the skin barrier: they limit transepidermal water loss, fill micro-cracks, promote hydration and bounce, and slow skin breakdown, for a healthy glow.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThe clinical study\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe MSM + collagen study was a randomized, double-blind, placebo-controlled trial involving 27 women aged 40 to 65 with a BMI under 35. Over 12 weeks, it examined how the combination of MSM and collagen could support the synthesis of collagen and elastin fibers in the dermis. Results:\u003c\/p\u003e\n\u003cul\u003e\u003cli\u003e19% improvement in dermal density with the collagen + MSM combination, compared with no change in the placebo group.\u003c\/li\u003e\u003cli\u003e40% more hydration and 12% less roughness. Adding MSM doubled the reduction in roughness compared with collagen alone.\u003c\/li\u003e\u003cli\u003eA 12% difference in skin texture with collagen + MSM compared with a more concentrated collagen-only supplement.\u003c\/li\u003e\u003cli\u003e21% fewer wrinkles. The study confirmed that wrinkles appear because of thinner, less hydrated skin; the MSM + collagen combination helped reverse this.\u003c\/li\u003e\u003c\/ul\u003e","brand":"Agent Nateur","offers":[{"title":"Default Title","offer_id":52395296883016,"sku":"AGEN-3050","price":134.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0925\/7123\/8728\/files\/duo-holi-mane-holi-radiance-agent-nateur-01.jpg?v=1769705755","url":"https:\/\/supirskin.com\/en\/products\/agent-nateur-duo-holi-mane-holi-radiance","provider":"Superskin","version":"1.0","type":"link"}